The Translational Breast Cancer Research Consortium was well represented at the 2021 SABCS Meeting. Presentations included:

Identifying Homologous Recombination Deficiency in Breast Cancer: Genomic Instability Score Thresholds Differ in Breast Cancer Subtypes (TBCRC 008); Abstract: #P5-13-09

The Breast PreCancer Atlas DCIS Genomic Signatures Define Biology and Correlate with Clinical Outcomes: an Analysis of TBCRC 038 and RAHBT Cohorts; Abstract: #GS4-07

Randomized Phase II Trial of Pembrolizumab/ Carboplatin vs Carboplatin Alone for Breast Cancer with Chest Wall Recurrence: TBCRC 044; Abstract: #OT1-18-08

Safety and Efficacy of a Tucatinib-Trastuzumab-Capecitabine Regimen for Treatment of Leptomeningeal Metastasis (LM) in HER2-Positive Breast Cancer: Results from TBCRC 049, a Phase 2 Non-Randomized Study; Abstract: #PD4-02